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Nasal Spray Formulations and Their Expanding Applications in Respiratory and Systemic Therapies
Nasal sprays are therapeutic formulations designed for targeted delivery of medications through the nasal mucosa. These products are widely used for managing conditions such as allergic rhinitis, sinusitis, congestion, and upper respiratory infections, offering rapid relief due to the highly vascularized nasal tissue.
Modern nasal sprays include corticosteroids, antihistamines, decongestants, and saline-based solutions. Additionally, intranasal delivery is gaining attention for systemic therapies, including migraine treatments, hormone administration, and vaccines, as it bypasses first-pass metabolism and enhances bioavailability.
Innovations in spray device design, particle size optimization, and mucoadhesive formulations improve patient compliance and therapeutic efficacy. With growing demand for non-invasive and rapid-acting treatments, nasal sprays represent a versatile and effective modality for both local and systemic therapy, enhancing patient outcomes across a variety of clinical indications.